ATM mouse Monoclonal Antibody(4G9), 100ul Custom RNA Oligos The developmental expression pattern of

The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis

Alternatively spliced transcript variants encoding different isoforms have been found for this gene

In tissues that do not express the mineralocorticoid receptor

Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways

It is highly homologous to the myelin protein zero and| in thymus-derived epithelial cell lines| is poorly soluble in nonionic detergents| strongly suggesting an association to the cytoskeleton

ATM mouse Monoclonal Antibody(4G9), 100ul Custom RNA Oligos The developmental expression pattern ofThe protein encoded by this gene belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of