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ASK1(Phospho-Thr845) Rabbit Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Mutations in TUBA1A cause lissencephaly

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ASK1(Phospho-Thr845) Rabbit Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Mutations in TUBA1A cause lissencephalyMitogen activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal regulated kinase (ERK) MAPK kinase (MKK or MEK) and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase MEKK phosphorylates and activates its downstream protein kinase MAPK kinase MEK which in turn activates MAPK. The kinases of these signaling cascades are highly conserved and homologs exist in yeast Drosophila and mammalian cells. MAPKKK5 contains 1 374

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Description

Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

The activation peptides of aspartic proteinases function as inhibitors of the protease active site

|sequence Translated as Cys

The protein belongs to the S27E family of ribosomal proteins

This protein methylates histone H3 at lysine residues 4 and 27| which represses gene transcription

ASK1(Phospho-Thr845) Rabbit Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Mutations in TUBA1A cause lissencephalyMitogen activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal regulated kinase (ERK) MAPK kinase (MKK or MEK) and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase MEKK phosphorylates and activates its downstream protein kinase MAPK kinase MEK which in turn activates MAPK. The kinases of these signaling cascades are highly conserved and homologs exist in yeast Drosophila and mammalian cells. MAPKKK5 contains 1 374

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