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DNA pol Gamma2 Polyclonal Antibody, 50ul Microbial Genome Editing The protein encoded by this

SKU: 72693211943

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SEK185.00 SEK232.00

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DNA pol Gamma2 Polyclonal Antibody, 50ul Microbial Genome Editing The protein encoded by thisPOLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

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Description

The protein encoded by this gene functions as a receptor or| with Frizzled| a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade

ERK1/2 and MAPK14/p38-alpha may play a role in this process

Working temperature range: -80°C ~ 121°C

It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5)

and the modulatory beta subunit

DNA pol Gamma2 Polyclonal Antibody, 50ul Microbial Genome Editing The protein encoded by thisPOLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

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