Mouse Dihydrofolate Reductase, DHFR ELISA Kit, 96T Cell Culture Plates The consequence of CD5 binding

The consequence of CD5 binding to its cognate receptor is still in question and likely plays a role in thymic selection

tissue specificity:Highly expressed in lymph node

This protein contains two conserved domains| an N-terminal RUN domain and a C-terminal DUF4206 domain

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an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains

Mouse Dihydrofolate Reductase, DHFR ELISA Kit, 96T Cell Culture Plates The consequence of CD5 bindingKey enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (PubMed: 25980602). Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (PubMed: 25980602). Binds its own mRNA.