STEAP1 Polyclonal Antibody, 50ul Organelle Studies This gene encodes a protein

This gene encodes a protein that plays a role in the regulation of glomerular permeability

and the assembly of small nuclear ribonucleoproteins

This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis

Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis|it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics)| abnormalities of brain development| and/or mental retardation of Down syndrome

The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity| and therefore is known as a dual specificity phosphatase

STEAP1 Polyclonal Antibody, 50ul Organelle Studies This gene encodes a proteinSTEAP1 is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell cell junctions.