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UB2R2 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) PTM:Phosphorylation at 'Thr-103' and 'Ser-573'

SKU: 73218884570

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UB2R2 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) PTM:Phosphorylation at 'Thr-103' and 'Ser-573'Protein kinase CK2 is a ubiquitous and pleiotropic Ser Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3 CDC34. Studies suggest that CK2 dependent phosphorylation of this ubiquitin conjugating enzyme functions by regulating beta TrCP substrate recognition and induces its interaction with beta TrCP, enhancing beta catenin degradation.

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Description

PTM:Phosphorylation at 'Thr-103' and 'Ser-573' is followed by proteasomal degradation

tissue specificity:Ubiquitously expressed

has yet to be determined

and MAPKAP kinase 2

Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype

UB2R2 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) PTM:Phosphorylation at 'Thr-103' and 'Ser-573'Protein kinase CK2 is a ubiquitous and pleiotropic Ser Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3 CDC34. Studies suggest that CK2 dependent phosphorylation of this ubiquitin conjugating enzyme functions by regulating beta TrCP substrate recognition and induces its interaction with beta TrCP, enhancing beta catenin degradation.

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