WRN Rabbit Polyclonal Antibody, 20ul Culture Media The paired box 4 gene

The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells

This protein corr

and binds specifically to MAP kinase kinase MAP2K1/MEK1

and may be involved in UV-induced signal transduction

Has no phosphatase 2A (PP2A) inhibitor activity (By similarity)

WRN Rabbit Polyclonal Antibody, 20ul Culture Media The paired box 4 geneThis gene encodes a member of the RecQ subfamily and the DEAH (Asp Glu Ala His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism including transcription replication recombination and repair. This protein contains a nuclear localization signal in the C terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity and is also a 3' to 5' exonuclease. Based