Stat5a Polyclonal Antibody, 100ul[BT-AP08640] Cell Culture TWEAK transcript is expressed broadly

TWEAK transcript is expressed broadly in many adult and fetal tissues

MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene

Mutations in SLC52A2 have been associated with Brown-Vialetto-Van Laere syndrome 2--an autosomal recessive progressive neurologic disorder characterized by deafness

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus| cytoplasm and mitochondria

A pseudogene of this gene is found on chromosome Y

Stat5a Polyclonal Antibody, 100ul[BT-AP08640] Cell Culture TWEAK transcript is expressed broadlyThe protein encoded by STAT5A (signal transducer and activator of transcription 5A) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands,