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UTF1 Polyclonal Antibody, 20ul Cell Senescence |disease:A chromosomal aberration involving NFKB2

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UTF1 Polyclonal Antibody, 20ul Cell Senescence |disease:A chromosomal aberration involving NFKB2The protein encoded by this gene is a leucine zipper containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. Found nearly exclusively in pluripotent cells, this protein can also serve as a transcriptional repressor.

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Description

|disease:A chromosomal aberration involving NFKB2 is found in a cutaneous T-cell leukemia (C-TCL) cell line

which suggests the tumor suppressor function of this gene

or form a type II integral membrane glycoprotein

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins

The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating actin reorganization downstream of the Rho family of small GTPases

UTF1 Polyclonal Antibody, 20ul Cell Senescence |disease:A chromosomal aberration involving NFKB2The protein encoded by this gene is a leucine zipper containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation of embryonic carcinoma and embryonic stem cells. Found nearly exclusively in pluripotent cells, this protein can also serve as a transcriptional repressor.

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