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IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody, 20ul Sealing Film Two transcript variants encoding distinct

SKU: 73944777689

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IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody, 20ul Sealing Film Two transcript variants encoding distinctThis gene encodes an intracellular receptor for inositol 1 4 5 trisphosphate. Upon stimulation by inositol 1 4 5 trisphosphate this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15 a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

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Description

Two transcript variants encoding distinct isoforms have been identified

ring-box 1 (Rbx1) and Cullin2 (Cul2)

Biosealing: Yes Available rotor adapters: A02P05

Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis

TNF receptor-associated factor 2 encoded by TRAF2 is a member of the TNF receptor associated factor (TRAF) protein family

IP3 Receptor(Phospho Tyr353) Rabbit Polyclonal Antibody, 20ul Sealing Film Two transcript variants encoding distinctThis gene encodes an intracellular receptor for inositol 1 4 5 trisphosphate. Upon stimulation by inositol 1 4 5 trisphosphate this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15 a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

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