PUR6 Rabbit Polyclonal Antibody, 100ul Cellular Cultivation & Health Management Overexpression of this gene in

Overexpression of this gene in COS7 cells stimulates translation

Multiple alternatively spliced transcript variants have been observed that encode distinct proteins

the encoded protein may not have any proteolytic activity

The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates

Polymorphisms in this gene may be associated with susceptibility for migraine headaches

PUR6 Rabbit Polyclonal Antibody, 100ul Cellular Cultivation & Health Management Overexpression of this gene inThis gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway and transcription of the two genes is coordinately regulated. The human genome