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ESM1 Polyclonal Antibody, 100ul Lysosome and with systemic non-neuropathic amyloidosis

SKU: 74608984730

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ESM1 Polyclonal Antibody, 100ul Lysosome and with systemic non-neuropathic amyloidosisThis gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

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Description

and with systemic non-neuropathic amyloidosis

Positively regulates the beta-catenin pathway (canonical Wnt signaling pathway) and is required for MCC-mediated repression of the beta-catenin pathway (PubMed: 24824780)

Members of the subfamily share similarity in sequence and splice sites

The protein encoded by CHST6 is an enzyme that catalyzes the transfer of a sulfate group to the GlcNAc residues of keratan

This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes

ESM1 Polyclonal Antibody, 100ul Lysosome and with systemic non-neuropathic amyloidosisThis gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

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