Presenilin 2(Phospho Ser330) Polyclonal Antibody, 50ul Cell Screening and Imaging Mutations in this gene have

Mutations in this gene have been associated with Andersen syndrome

The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein

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members of the TNF receptor superfamily

Presenilin 2(Phospho Ser330) Polyclonal Antibody, 50ul Cell Screening and Imaging Mutations in this gene haveAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP. Also,