TERT Polyclonal Antibody, 50ul[BT-AP14866] Site-directed Mutagenesis The protein encoded by DOK2

The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

At least one pseudogene has been identified at 17p12-p11

These zinc finger domains

also known as 5-azacytidine-induced protein 1

This gene encodes a forkhead transcription factor

TERT Polyclonal Antibody, 50ul[BT-AP14866] Site-directed Mutagenesis The protein encoded by DOK2Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres.