DSG4 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) The encoded protein functions through

The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development

Existing as four alternatively spliced isoforms

This gene belongs to the family of reticulon encoding genes

Multiple pseudogenes have been identified for this gene

Members of the WD40 repeat family are key components of many essential biologic functions

DSG4 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) The encoded protein functions throughThis gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth.