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TIMP-3 Polyclonal Antibody, 50ul Sealing Film Ready for a bold challenge

SKU: 75559878340

4.8
USD185.00 USD230.00

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TIMP-3 Polyclonal Antibody, 50ul Sealing Film Ready for a bold challengeTIMP3 belongs to the TIMP gene family. Metalloproteinase inhibitor 3 encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's

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Description

Ready for a bold challenge

Mutations in this gene cause hypoglobulinemia and absent B cells

Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes

plays a role in fibroblast transformation by BCR-ABL

This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis

TIMP-3 Polyclonal Antibody, 50ul Sealing Film Ready for a bold challengeTIMP3 belongs to the TIMP gene family. Metalloproteinase inhibitor 3 encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's

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