HDAC2(Phospho Ser394) Polyclonal Antibody, 100ul Microplate Mixer RCBTB1 maps to a region

RCBTB1 maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies

and in a dimeric or multimeric form at the cell surface and in extracellular matrix

Alternative splicing results in multiple transcript variants and protein isoforms

It may be a critical substrate for p210(bcr/abl)| a chimeric protein whose presence is associated with CML

which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS)

HDAC2(Phospho Ser394) Polyclonal Antibody, 100ul Microplate Mixer RCBTB1 maps to a regionThis gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc finger transcription factor. Thus, it plays an important