NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance L-plastin has been found in

L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues

This gene is imprinted in the brain

The encoded protein plays a role in eye development

Multiple processed pseudogenes derived from this gene are present in the genome

and has been found to be overexpressed in 10% of clear cell renal carcinomas

NDE1 Polyclonal Antibody, 100ul Cell Culture & Maintenance L-plastin has been found inThis gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain