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IRAK-1(Phospho Ser376) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Inhibitory receptors regulate the immune

SKU: 75887026773

4.7
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IRAK-1(Phospho Ser376) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Inhibitory receptors regulate the immuneThis gene encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self

which suggests the antiapoptotic function of this gene in cells

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

thought to be involved in the stimulation of cell proliferation

One isoform lacks the intermembrane region and is secreted outside the cell

IRAK-1(Phospho Ser376) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) Inhibitory receptors regulate the immuneThis gene encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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