EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 20ul Cell Culture Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been noted for this gene

and transcriptional regulatory properties

Member RAS Oncogene Family) is a Protein Coding gene

The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity

The protein encoded by this gene contains a C-terminal RING finger domain

EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 20ul Cell Culture Alternatively spliced transcript variants encodingThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.