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PKD2(Phospho Ser876) Polyclonal Antibody, 100ul Protein Research WEE1 (WEE1 G2 checkpoint kinase)

SKU: 75990666525

4.4
PLN141.00 PLN170.00

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PKD2(Phospho Ser876) Polyclonal Antibody, 100ul Protein Research WEE1 (WEE1 G2 checkpoint kinase)The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding

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Description

WEE1 (WEE1 G2 checkpoint kinase) encodes a nuclear protein

This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A

Telomerase expression plays a role in cellular senescence| as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres

The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus

including eotaxin (CCL11)

PKD2(Phospho Ser876) Polyclonal Antibody, 100ul Protein Research WEE1 (WEE1 G2 checkpoint kinase)The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding

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