CD6 Polyclonal Antibody, 20ul[BT-AP01988] Tubes COL4A4 is organized in a

COL4A4 is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter

suggesting a role for CER in the pathology of these diseases

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CD6 Polyclonal Antibody, 20ul[BT-AP01988] Tubes COL4A4 is organized in aCLN6 (ceroid lipofuscinosis, neuronal 6, late infantile, variant) is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post translationally modified proteins in lysosomes. The primary defect in NCL disorders is