Histone H2B Polyclonal Antibody, 100ul[BT-AP04030] Filtration The non-SMC condensin I complex

The non-SMC condensin I complex subunit H encoded by NCAPH is associated with mitotic chromosomes

Mutations in this gene have been associated with Hodgkin lymphoma

At least three alternatively spliced variants encoding distinct proteins have been reported

is expressed primarily in the brain

This gene was identified by its oncogenic transforming activity

Histone H2B Polyclonal Antibody, 100ul[BT-AP04030] Filtration The non-SMC condensin I complexHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.