PK1IP Polyclonal Antibody, 20ul ssDNA Synthesis The encoded mechanosensing protein contains

The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension| resulting in the reconfiguration of cadherin-actin filament connections

and then stimulates transcription of androgen responsive genes

This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene

Rab5 and Rab14

The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements

PK1IP Polyclonal Antibody, 20ul ssDNA Synthesis The encoded mechanosensing protein containsNegatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N terminal regulatory domain. PAK1IP1 also binds to the N terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.,Contains 5 WD