GIT2 Polyclonal Antibody, 100ul Antibody Humanization transformation

transformation

Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis

Phosphorylates and activates MAP2K4 and MAP2K6| which in turn activate the JNK and p38 MAP kinases| respectively

This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression

This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport

GIT2 Polyclonal Antibody, 100ul Antibody Humanization transformationGIT2 encodes a member of the GIT protein family, ARF GTPase activating protein GIT2, which interact with G protein coupled receptor kinases and possess ADP ribosylation factor (ARF) GTPase activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins.