IFI-16 Polyclonal Antibody, 100ul Shaker&Mixing mitochondrial complex IV deficiency

mitochondrial complex IV deficiency

Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres

An important paralog of this gene is NAA16

A related pseudogene has been defined on chromosome X

This protein localizes to the centrosome and has a function in microtubular stabilization

IFI-16 Polyclonal Antibody, 100ul Shaker&Mixing mitochondrial complex IV deficiencyIFI16 encodes a member of the HIN 200 (hematopoietic interferon inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma 1. It modulates p53 function, and inhibits cell growth in the Ras Raf signaling pathway.