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PABP3 Polyclonal Antibody, 50ul Molecular Biology Multiple alternatively spliced transcript variants

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PABP3 Polyclonal Antibody, 50ul Molecular Biology Multiple alternatively spliced transcript variantsPABPC3 encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. PABPC3 is part of a small gene family including three protein coding genes and

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Description

Multiple alternatively spliced transcript variants have been described

NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes| platelet dense granules| and lysosomes

Triggers mitochondrial apoptosis during pachytene spermatocyte differentiation

transport and localization

PABP3 Polyclonal Antibody, 50ul Molecular Biology Multiple alternatively spliced transcript variantsPABPC3 encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. PABPC3 is part of a small gene family including three protein coding genes and

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