Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The functions of human sirtuins

The functions of human sirtuins have not yet been determined

Impaired spindle checkpoint function has been found in many forms of cancer

The lymphotoxin-alpha

The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription

PTM:Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding

Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis The functions of human sirtuinsMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.