TIRAP(Phospho Tyr86) Polyclonal Antibody, 20ul Cell Culture Dishes Their C-terminal EVH2 domain mediates

Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin

Defect in GIPR thus may contribute to the pathogenesis of diabetes

Mutations of this gene are associated with Seckel syndrome

Arginine methylation in these regions has no effect on this binding

Belongs to the endophilin family

TIRAP(Phospho Tyr86) Polyclonal Antibody, 20ul Cell Culture Dishes Their C-terminal EVH2 domain mediatesThe innate immune system recognizes microbial pathogens through Toll like receptors (TLRs), which identify pathogen associated molecular patterns. Different TLRs recognize different pathogen associated molecular patterns and all TLRs have a Toll interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It