YAP Polyclonal Antibody, 20ul[BT-AP09632] sgRNA Library Construction Mutations in COL4A1 cause porencephaly

Mutations in COL4A1 cause porencephaly

such as cell division and regulation of insulin sensitivity

An important paralog of this gene is JMJD7-PLA2G4B

with the protein encoded by this gene representing the beta subunit

this protein does not contain a C-terminal PDZ domain-binding motif

YAP Polyclonal Antibody, 20ul[BT-AP09632] sgRNA Library Construction Mutations in COL4A1 cause porencephalyYAP1 encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.