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CDKN3 Polyclonal Antibody, 100ul[BT-AP07567] Proteases induction:Down-regulated in cancer pancreatic cells

SKU: 79192250205

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CDKN3 Polyclonal Antibody, 100ul[BT-AP07567] Proteases induction:Down-regulated in cancer pancreatic cellsThe protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this

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Description

induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis

The enzyme is known to metabolize many xenobiotics

Gene Ontology (GO) annotations related to this gene include GTPase activator activity

14-dihydro-prostaglandin E2

ATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins

CDKN3 Polyclonal Antibody, 100ul[BT-AP07567] Proteases induction:Down-regulated in cancer pancreatic cellsThe protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this

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