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PGP9.5 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes This gene and the orthologous

SKU: 79337957743

4.6
PLN97.20 PLN125.20

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PGP9.5 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes This gene and the orthologousThe protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

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Description

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes

elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport

Seems to prevent the degeneration of motor axons after axotomy

and this kinase itself can be phoshorylated

Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum

PGP9.5 Rabbit Polyclonal Antibody, 20ul Metabolic enzymes This gene and the orthologousThe protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

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