Bcl-2 Polyclonal Antibody, 50ul[BT-AP00857] Virus Packaging This encoded protein is expressed

This encoded protein is expressed on Natural killer (NK)

The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis

Initially assumed to be a pseudogene

but is upregulated upon activation of lymphocytes

The protein has substantial GAP activity towards several Rho-family GTPases in vitro

Bcl-2 Polyclonal Antibody, 50ul[BT-AP00857] Virus Packaging This encoded protein is expressedBCL2 encodes an integral outer mitochondrial membrane protein (BCL2, apoptosis regulator) that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.