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SNX3 Polyclonal Antibody, 100ul Petri Dishes Studies in rats found the

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SNX3 Polyclonal Antibody, 100ul Petri Dishes Studies in rats found theSNX3 (sorting nexin 3) encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol 3 phosphate, and is involved in protein trafficking. A pseudogene of SNX3 is present on the sex chromosomes.

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Description

Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation

The encoded protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein

Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer

This suggests this gene product may function as a tumor suppressor

This gene encodes a member of the inwardly rectifying potassium channel family of proteins

SNX3 Polyclonal Antibody, 100ul Petri Dishes Studies in rats found theSNX3 (sorting nexin 3) encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol 3 phosphate, and is involved in protein trafficking. A pseudogene of SNX3 is present on the sex chromosomes.

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