P3C2A Polyclonal Antibody, 20ul Peptide Synthesis Mutations in this gene have

Mutations in this gene have been associated with hepatocellular carcinoma

Alternatively spliced transcript variants encoding different isoforms have been described

RSU1 (Ras suppressor protein 1) encodes a protein that is involved in the Ras signal transduction pathway

and dementia

ADAM10 encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin

P3C2A Polyclonal Antibody, 20ul Peptide Synthesis Mutations in this gene haveThe protein encoded by this gene belongs to the phosphoinositide 3 kinase (PI3K) family. PI3 kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C terminal C2 domain, a characteristic of class II PI3 kinases. C2 domains act as calcium dependent phospholipid binding