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NKp30 Polyclonal Antibody, 20ul[BT-AP06043] Cell Screening and Imaging Mutations in this gene have

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NKp30 Polyclonal Antibody, 20ul[BT-AP06043] Cell Screening and Imaging Mutations in this gene haveThe natural cytotoxicity triggering receptor 3 encoded by NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3 zeta (CD247), a T cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

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Description

Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14

This protein has been shown to interact with tumor suppressor protein Rb and the expression of CCND1 is regulated positively by Rb

Through the interaction with ILK

The human CD72 gene maps to chromosome 9p13

It functions either as a monomer

NKp30 Polyclonal Antibody, 20ul[BT-AP06043] Cell Screening and Imaging Mutations in this gene haveThe natural cytotoxicity triggering receptor 3 encoded by NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3 zeta (CD247), a T cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

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