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p53 Polyclonal Antibody, 20ul[BT-AP06819] Transporters The protein encoded by CKLF

SKU: 82197695989

4.7
DKK97.20 DKK117.20

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p53 Polyclonal Antibody, 20ul[BT-AP06819] Transporters The protein encoded by CKLFTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

The protein encoded by CKLF is a potent chemoattractant for neutrophils

Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of CRHR1

Three transcript variants encoding different isoforms have been found for CYB5A

YOD1 deubiquitinase by YOD1 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain

GNL1 is telomeric to HLA-B and HLA-C

p53 Polyclonal Antibody, 20ul[BT-AP06819] Transporters The protein encoded by CKLFTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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