Stat3 Polyclonal Antibody, 100ul[BT-AP01664] Protein Modification Mutations in CTSA are associated

Mutations in CTSA are associated with galactosialidosis

The transforming acidic coiled-coil-containing protein 3 is a motor spindle protein that may play a role in stabilization of the mitotic spindle

which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III

RNA splicing

An important paralog of this gene is SYNE2

Stat3 Polyclonal Antibody, 100ul[BT-AP01664] Protein Modification Mutations in CTSA are associatedThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.