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ITA10 Polyclonal Antibody, 50ul Organelle Studies together with MITF

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ITA10 Polyclonal Antibody, 50ul Organelle Studies together with MITFIntegrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP 2epsilon and Ets 1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants.

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Description

together with MITF

This enzyme is involved in creatine biosynthesis| whereby it catalyzes the transfer of a guanido group from L-arginine to glycine| resulting in guanidinoacetic acid| the immediate precursor of creatine

induction:Up-regulated by endothelial cells when exposed to tumor conditional media

The encoded protein forms the ion pore region of the voltage-gated sodium channel

There are numerous pseudogenes of this gene on multiple chromosomes

ITA10 Polyclonal Antibody, 50ul Organelle Studies together with MITFIntegrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP 2epsilon and Ets 1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants.

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