CD43 Rabbit Polyclonal Antibody, 50ul Peptide Modification The product of this gene

The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal| followed by two fibronectin type-III motifs

Interactions have been observed with Bcl-2

It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines

It influences cellular physiologic processes by regulating the expression of downstream target genes

CD43 Rabbit Polyclonal Antibody, 50ul Peptide Modification The product of this geneThe protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes T lymphocytes monocytes granulocytes and some B lymphocytes. It may be part of a physiologic ligand receptor complex involved in T cell activation. During T cell activation this protein is actively removed from the T cell APC (antigen presenting cell) contact site suggesting a negative regulatory role in adaptive immune response.