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Smad3 Polyclonal Antibody, 50ul[BT-AP08391] Bottles possibly tissue-specific alternative splicing events

SKU: 82657637508

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Smad3 Polyclonal Antibody, 50ul[BT-AP08391] Bottles possibly tissue-specific alternative splicing eventsThe protein encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of

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Description

possibly tissue-specific alternative splicing events

It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers

The string of histidine residues binds to several types of immobilized metal ions

The hes related family bHLH transcription factor with YRPW motif 2 forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription

and then form homodimers

Smad3 Polyclonal Antibody, 50ul[BT-AP08391] Bottles possibly tissue-specific alternative splicing eventsThe protein encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of

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