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KCNE4 Polyclonal Antibody, 100ul Reservoirs a phosphotidylinositol-3 kinase binding site

SKU: 82963205418

4.4
SEK141.00 SEK180.00

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KCNE4 Polyclonal Antibody, 100ul Reservoirs a phosphotidylinositol-3 kinase binding siteVoltage gated potassium (Kv) channels represent the most complex class of voltage gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage gated, isk related subfamily. This member

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Description

a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif

and so it is thought to play an important role in cellular signal transduction

Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene

A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes

subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males

KCNE4 Polyclonal Antibody, 100ul Reservoirs a phosphotidylinositol-3 kinase binding siteVoltage gated potassium (Kv) channels represent the most complex class of voltage gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage gated, isk related subfamily. This member

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