VRK2 Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene are

Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females

Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons

The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments

An important paralog of this gene is NEK2

The protein encoded by this gene localizes to focal adhesions

VRK2 Polyclonal Antibody, 50ul Virus Packaging Mutations in this gene areVRK2 (vaccinia related kinase 2) encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in VRK2 have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.