CE104 Rabbit Polyclonal Antibody, 100ul Metabolic enzymes In humans| polymorphisms in this

In humans| polymorphisms in this gene are associated with variation in human height and osteoarthritis

The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers

Two transcript variants| one protein-coding and the other non-protein coding| have been found for this gene

In addition| using a separate promoter in an intron in the 3' region| it encodes telokin| a small protein identical in sequence to the C-terminus of myosin light chain kinase| that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments

and the testis

CE104 Rabbit Polyclonal Antibody, 100ul Metabolic enzymes In humans| polymorphisms in thisThis gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino terminal hydrophobic domains, two glycosylation sites, four cysteine rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium.