TTC22 Rabbit Polyclonal Antibody, 20ul Sample Library Tubes IRX3 is a member of

IRX3 is a member of the Iroquois homeobox gene family (see IRX1

as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele

DNA damage inducible transcript 3 functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members

contains structural domains similar to beta chains

PKC also serves as the receptor for phorbol esters| a class of tumor promoters

TTC22 Rabbit Polyclonal Antibody, 20ul Sample Library Tubes IRX3 is a member ofThis gene encodes a protein with seven tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein protein interactions and chaperone activity. Alternatively spliced transcript variants have been found for this gene.