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PBIP1 Rabbit Polyclonal Antibody, 50ul Shaker&Mixing and it is present in

SKU: 8432642048

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PBIP1 Rabbit Polyclonal Antibody, 50ul Shaker&Mixing and it is present inThe protein encoded by this gene interacts with the PBX1 homeodomain protein inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein which is primarily cytosolic but can shuttle to the nucleus also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer brain tumors and lung cancer. Several transcript variants encoding different isoforms have been found for

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Description

and it is present in a cluster with other family members on chromosome 22

DNA-binding domain

NBL1 product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins

The encoded protein also promotes transcription at the c-fos gene

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases

PBIP1 Rabbit Polyclonal Antibody, 50ul Shaker&Mixing and it is present inThe protein encoded by this gene interacts with the PBX1 homeodomain protein inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein which is primarily cytosolic but can shuttle to the nucleus also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer brain tumors and lung cancer. Several transcript variants encoding different isoforms have been found for

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