ECE1 Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) DNM1L encodes a member of

DNM1L encodes a member of the dynamin superfamily of GTPases

producing an elongated polyglutamine tract in the corresponding protein

EIF4E and EIF4G1/EIF4G3

This gene lies in a region of chromosome 2 that surrounds the site where two ancestral chromosomes fused to form human chromosome 2

and a key role in cardiovascular homeostasis

ECE1 Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) DNM1L encodes a member ofThe protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.