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Ku-70 Polyclonal Antibody, 100ul[BT-AP04891] Serum & Sample Tubes Acts as a GDP-dissociation stimulator

SKU: 85938029025

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Ku-70 Polyclonal Antibody, 100ul[BT-AP04891] Serum & Sample Tubes Acts as a GDP-dissociation stimulatorThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them

Mutations in this gene are associated with the disorders multiple endocrine neoplasia

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The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains

Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis

Ku-70 Polyclonal Antibody, 100ul[BT-AP04891] Serum & Sample Tubes Acts as a GDP-dissociation stimulatorThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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