IGF-IR Polyclonal Antibody, 20ul[BT-AP04398] Custom Peptide Synthesis CUL4B is a member of

CUL4B is a member of the cullin family

plays an important role in replication-dependent chromatin assembly

This protein also binds to mutant huntingtin (mHtt)

and is thought to regulate cell motility

Among its related pathways are Metabolism of proteins and O-linked glycosylation

IGF-IR Polyclonal Antibody, 20ul[BT-AP04398] Custom Peptide Synthesis CUL4B is a member ofIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms