Rat Progranulin, PGRN ELISA Kit, 96T Nucleic Acid Isolation & Purification GO annotations related to this

GO annotations related to this gene include binding and RNA polymerase binding

It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes

PubMed: 25173806)

SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes

thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery

Rat Progranulin, PGRN ELISA Kit, 96T Nucleic Acid Isolation & Purification GO annotations related to thisSecreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation (By similarity). Regulates protein trafficking to lysosomes and, also the activity of lysosomal enzymes (By similarity). Facilitates also the acidification of lysosomes, causing degradation of mature CTSD by CTSB (By similarity). In addition, functions as wound related growth factor that acts